Distal Tubulopathy. Gitelman Syndrome

Pediatričeskaâ Farmakologiâ

Tatyana V. Sergeeva¹  Leyla S. Namazova-Baranova²  Alexander A. Baranov²  Vladimir K. Tatochenko²  Maya D. Bakradze³  Tea V. Margieva³  Olga I. Zrobok³  Tatiana V. Vashurina³  Olga V. Chumakova³  Svetlana S. Paunova³  Elena N. Tsygina³  Irina N. Lupan³  Nurali Z. Zokirov³  Alexey N. Tsygin⁴  Mikhail Yu. Kagan⁵  Olga V. Komarova⁶ 

[1] Pirogov Russian National Research Medical University;Central Clinical Hospital of the Russian Academy of Sciences;National Medical Research Center of Children's Health;Regional Children's Clinical Hospital;South Ural State Medical University;The Central Pediatric Clinical Hospital of FMBA of Russia;

关键词: tubulopathy;    gitelman syndrome;    diagnostics;    treatment;    clinical recommendations;    children;   

DOI  :  10.15690/pf.v16i3.2025

来源: DOAJ

【 摘 要 】

The clinical recommendations on management of children with Gitelman syndrome developed by the experts of the Union of pediatricians of Russia are presented in this article. Gitelman syndrome is a dysfunction of distal renal tubules with further development of hypomagnesemia, hypocalciuria and secondary aldosteronism which determine hypokalemia and metabolic alkalosis. Features of epidemiology, etiology and pathogenesis, disease progression, differential diagnostics and evidence-based treatment are presented.

【 授权许可】

Unknown