DegoViz: An Interactive Visualization Tool for a Differentially Expressed Genes Heatmap and Gene Ontology Graph

Applied Sciences

Kyungwon Lee¹  Sejong Oh¹  Somyung Oh²  Junghyeon Ha³ 

[1] Department of Digital Media, Ajou University, Suwon 16499, Korea;;Department of Visualization, Texas A&M University, College Station, TX 77843, USA;

关键词: differentially expressed gene;    gene ontology;    heatmap;    microarray;    visualization;   

DOI  :  10.3390/app7060543

来源: DOAJ

【 摘 要 】

Microarray is a general scheme to identify differentially expressed genes for a target concept and can be used for biology. The output is presented utilizing a heatmap that biologists analyze in related terms of gene ontology to determine the characteristics of differentially expressed genes. In this paper, we propose an integrated visualization tool for a heatmap and gene ontology graph. Most of the previous methods used were static and none of them were combined. The proposed visualization tool integrates these and provides users with an interactive management ability. Users can easily identify and confirm related terms of gene ontology for given differentially expressed genes. Further, the proposed tool visualizes the connections between genes on the heatmap and gene ontology graph. Therefore, the proposed tool can be used for precision healthcare.

【 授权许可】

Unknown