Phyllodes tumor of the breast: Wolf inside the sheep’s skin!

Oncobiology and Targets

Monali Swain¹  Tabassum Wadasadawala¹  Jyoti Bajpai² 

[1] Department of Radiation Oncology;Medical Oncology, Tata Memorial Center, Mumbai;

关键词: Phyllodes tumor;    adjuvant therapy;    breast;    malignant phyllodes;   

DOI  :  10.18639/ONBT.2016.03.1257

来源: DOAJ

【 摘 要 】

Phyllodes tumor, previously known as cystosarcoma phyllodes, is a rare fibro-epithelial tumor of breast constituting <1% of all the breast tumors. It is classified into benign, borderline, and malignant subtypes depending upon the histological criteria defined by the World Health Organization and also has an independent prognostic significance. Accurate pretreatment histological diagnosis is important for the optimal management of phyllodes tumor so that low recurrence rates, improved survival, and optimal long-term cosmetic result can be achieved. Despite surgery being the standard of care, the best type of surgery for each histological type is yet to be defined. The higher rate of local recurrence after surgery alone in borderline and malignant phyllodes tumor raises the question regarding the need of adjuvant treatment, especially radiotherapy, which remains underutilized. The perspective of the current review is to provide the state-of-the-art management of phyllodes tumor of the breast and highlight the risk factors associated with recurrence.

【 授权许可】

Unknown