Tortuosity in tumours: The need of combining multi-phase flows with machine learning tools

Results in Engineering

Soledad Le Clainche¹  Ana Pariente²  Rodrigo Abadía-Heredia²  José M. Pérez² 

[1] Corresponding author.;E.T.S.I. Aaeronáutica y del Espacio, Universidad Politécnica de Madrid, Pza. Cardenal Cisneros, E-28040, Madrid, Spain;

关键词: Tortuosity;    Multiphase flow;    Flow topology;   

DOI  :  

来源: DOAJ

【 摘 要 】

This article presents a preliminary approximation of the effect in blood flow produced by tortuosity in the blood vessels. This roughness is related to certain diseases (such as tumours) and the modelling of the flow properties can help to characterize the existence of such diseases. Malignancy provokes local changes to vessel shape and characteristic vessel tortuosity appears early during tumour development. Numerical simulations have been carried out, where the elastic behaviour modelling the surface of blood vessels has been represented using several geometries with different wavy shapes. The complexity of the topology patterns, which could be related with the different particle paths found in different geometries, encourages to continue this research using novel machine learning tools to predict and connect the main flow instabilities with the tumour evolution.

【 授权许可】

Unknown