A unified approach to the important protein kinase inhibitor balanol and a proposed analogue

Beilstein Journal of Organic Chemistry

Tapan Saha¹  Ratnava Maitra¹  Shital K. Chattopadhyay¹ 

[1] Department of Chemistry, University of Kalyani, Kalyani - 741235, West Bengal, India;

关键词: azepane;    balanol;    Garner’s aldehyde;    PKC inhibitor;    ring-closing metathesis;   

DOI  :  10.3762/bjoc.9.327

来源: DOAJ

【 摘 要 】

A common approach to the important protein kinase inhibitor (−)-balanol and an azepine-ring-modified balanol derivative has been developed using an efficient fragment coupling protocol which proceeded in good overall yield.

【 授权许可】

Unknown