Physiological Effects of Neonicotinoid Insecticides on Non-Target Aquatic Animals—An Updated Review

International Journal of Molecular Sciences

Chung-Der Hsiao¹  Jong-Chin Huang²  Kelvin H.-C. Chen²  Hong-Thih Lai³  Nemi Malhotra⁴  Tzong-Rong Ger⁴  Boontida Uapipatanakul⁵  Marri Jmelou M. Roldan⁶  Allan Patrick G. Macabeo⁷ 

[1] Center for Nanotechnology, Chung Yuan Christian University, Chung-Li 320314, Taiwan;Department of Applied Chemistry, National Pingtung University, Pingtung 900391, Taiwan;Department of Aquatic Biosciences, National Chiayi University, 300 University Rd., Chiayi 60004, Taiwan;Department of Biomedical Engineering, Chung Yuan Christian University, Chung-Li 320314, Taiwan;Department of Chemistry, Faculty of Science and Technology, Rajamangala University of Technology, Thanyaburi 12110, Thailand;Faculty of Pharmacy, The Graduate School, University of Santo Tomas, Espana Blvd., Manila 1015, Philippines;Laboratory for Organic Reactivity, Discovery and Synthesis (LORDS), Research Center for the Natural and Applied Sciences, University of Santo Tomas, Espana Blvd., Manila 1015, Philippines;

关键词: neonicotinoid;    aquatic animal;    toxicity;    non-target species;   

DOI  :  10.3390/ijms22179591

来源: DOAJ

【 摘 要 】

In this paper, we review the effects of large-scale neonicotinoid contaminations in the aquatic environment on non-target aquatic invertebrate and vertebrate species. These aquatic species are the fauna widely exposed to environmental changes and chemical accumulation in bodies of water. Neonicotinoids are insecticides that target the nicotinic type acetylcholine receptors (nAChRs) in the central nervous systems (CNS) and are considered selective neurotoxins for insects. However, studies on their physiologic impacts and interactions with non-target species are limited. In researches dedicated to exploring physiologic and toxic outcomes of neonicotinoids, studies relating to the effects on vertebrate species represent a minority case compared to invertebrate species. For aquatic species, the known effects of neonicotinoids are described in the level of organismal, behavioral, genetic and physiologic toxicities. Toxicological studies were reported based on the environment of bodies of water, temperature, salinity and several other factors. There exists a knowledge gap on the relationship between toxicity outcomes to regulatory risk valuation. It has been a general observation among studies that neonicotinoid insecticides demonstrate significant toxicity to an extensive variety of invertebrates. Comprehensive analysis of data points to a generalization that field-realistic and laboratory exposures could result in different or non-comparable results in some cases. Aquatic invertebrates perform important roles in balancing a healthy ecosystem, thus rapid screening strategies are necessary to verify physiologic and toxicological impacts. So far, much of the studies describing field tests on non-target species are inadequate and in many cases, obsolete. Considering the current literature, this review addresses important information gaps relating to the impacts of neonicotinoids on the environment and spring forward policies, avoiding adverse biological and ecological effects on a range of non-target aquatic species which might further impair the whole of the aquatic ecological web.

【 授权许可】

Unknown