Genome of a chronic osteitis-causing Clostridium tetani

New Microbes and New Infections

D. Raoult¹  P.-Y. Levy¹  M. Million¹  P. Brouqui¹  P.-E. Fournier¹  C. Blanc-Tailleur¹  O. Croce¹ 

[1] Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UM 63, CNRS 7278, IRD 198, INSERM U1095, Institut Hospitalo-Universitaire Méditerranée Infection, Faculté de Médecine, Aix-Marseille Université, 27 Boulevard Jean Moulin, 13005, Marseille, France;

关键词: Chronic osteitis;    Clostridium tetani;    genome;    neurotoxin;    tetanospasmin;   

DOI  :  10.1002/2052-2975.27

来源: DOAJ

【 摘 要 】

We sequenced the genome of a Clostridium tetani strain that caused chronic tibial osteitis without any clinical sign of tetanus in a 26-year-old man previously vaccinated against this disease. The genome contained a plasmid that harboured the tetX-tetR tetanospasmin operon, and was highly similar to that of a tetanus-causing strain.

【 授权许可】

Unknown