The nuclear functions of long noncoding RNAs come into focus

Non-coding RNA Research

Chuan Huang¹  Jiamei Lin¹  Zhenxing Song²  Zhengguo Li² 

[1] Center of Plant Functional Genomics, Institute of Advanced Interdisciplinary Studies, Chongqing University, Chongqing, 401331, China;School of Life Sciences, Chongqing University, Chongqing, 401331, China;

关键词: MALAT1;    NEAT1;    XIST;    Circular RNA;    RNA-Binding protein;    Nucleus;   

DOI  :  

来源: DOAJ

【 摘 要 】

Long noncoding RNAs (lncRNAs), defined as untranslated and tightly-regulated transcripts with a length exceeding 200 nt, are common outputs of the eukaryotic genome. It is becoming increasingly apparent that many lncRNAs likely serve as important regulators in a variety of biological processes. In particular, some of them accumulate in the nucleus and function in diverse nuclear events, including chromatin remodeling, transcriptional regulation, RNA processing, DNA damage repair, etc. Here, we unite recent progresses on the functions of nuclear lncRNAs and provide insights into the future research directions of this field.

【 授权许可】

Unknown