Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report

Clinical Case Reports

Shinichiro Kashiwagi¹  Kiyoshi Maeda²  Tatsunari Fukuoka³  Yasuhito Iseki³  Yuki Okazaki³  Masatsune Shibutani³  Hisashi Nagahara³  Kosei Hirakawa³  Masaichi Ohira³ 

[1] Department of Breast and Endocrine Surgery Osaka City University Graduate School of Medicine Osaka Japan;Department of Gastroenterological Surgery Osaka City General Hospital Osaka Japan;Department of Gastroenterological Surgery Osaka City University Graduate School of Medicine Osaka Japan;

关键词: colorectal cancer;    febrile neutropenia;    FTD/TPI;    neutropenia;    pancytopenia;   

DOI  :  10.1002/ccr3.5544

来源: DOAJ

【 摘 要 】

Abstract Although the incidence of hematological toxicity due to Trifluridine/tipiracil (FTD/TPI) treatment is high, the incidence of severe adverse events has been reported to be relatively low. However, it should be noted that patients with renal impairment are prone to severe hematological adverse events.

【 授权许可】

Unknown