Artificial stone‐associated silicosis: clinical‐pathological‐radiological correlates of disease

Respirology Case Reports

Catriona McLean¹  Ryan Hoy²  Kovi Levin² 

[1] Anatomical Pathology Alfred Health Melbourne Australia;Respiratory Medicine Alfred Health Melbourne Australia;

关键词: Alveolar proteinosis;    artificial stone;    interstitial lung disease;    occupational lung disease;    silicosis;   

DOI  :  10.1002/rcr2.470

来源: DOAJ

【 摘 要 】

Occupational lung disease secondary to inhalation of silica particles is variable and potentially life‐threatening. As the artificial stone industry has grown over the last two decades, the development of silicosis has been seen to accelerate and behave differently to chronic silicosis. In this case report, we present two patients who underwent lung transplantation for silicosis at the Alfred Hospital, both with predominantly artificial stone masonry exposure. We have identified the presence of both fibrotic/nodular silicosis and conspicuous alveolar proteinosis within the same lung parenchyma of both patients. We then demonstrate the radiological and histopathological correlates of disease; the first time this has been shown clearly in the literature.

【 授权许可】

Unknown