期刊论文详细信息
Journal of Mind and Medical Sciences | |
Hepatocarcinoma with tumor thrombus occupying the right atrium and portal vein in a patient with hereditary hemochromatosis and liver cirrhosis | |
Angela Cozma1  Simina Tarmure Sarlea1  Vasile Negrean1  Olga Hilda Orasan1  Dorel Sampelean2  Flaviu Muresan3  Ovidiu Fabian3  Laura Urian4  Iulia Breaban5  Sorina Cezara Secara5  Andreea Maria Stefan6  Anca Mihailov7  | |
[1]Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 4th Department of Internal Medicine, Cluj-Napoca, Romania | |
[2]Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 4th Department of Internal Medicine, Cluj-Napoca, Romania | |
[3]Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 4th Department of Surgery, ClujNapoca, Romania | |
[4]Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Department of Hematology, Cluj-Napoca, Romania | |
[5]Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania | |
[6]Prof. Dr. Octavian Fodor, Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania | |
[7]Railway Hospital, 4th Surgical Department, Cluj-Napoca, Romania | |
关键词: right atrial tumor thrombus; hepatocellular carcinoma; hereditary hemochromatosis; | |
DOI : 10.22543/7674.52.P300304 | |
来源: DOAJ |
【 摘 要 】
We present the case of a 46-year old patient with Child-Pugh class C cirrhosis with MEDL-Score 16, and hepatocellular carcinoma invading the inferior vena cava and the right atrium. The etiology of cirrhosis is type 1 hereditary hemochromatosis with positive HFE C282Y/C282Y and H63D/H63D mutations. A systematic review of the literature was performed and only 30 cases of hepatocellular carcinoma with tumor thrombosis extending into the right atrium have been described. To our knowledge, this is the first case that evidences the presence in hereditary hemochromatosis of hepatocellular carcinoma with atypical invasion into the right atrium. Screening of patients with a family history of hereditary hemochromatosis allows detection of the disease in the asymptomatic phase, allowing initiation of early therapy and improved prognosis.【 授权许可】
Unknown