Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses

Parasites & Vectors

RADAM-LAC Research Team¹  Silvia Rondón²  Camila González²  Cielo León²  María C. Carrasquilla²  Mario I. Ortiz²  Juan M. Cordovez³  Benoit Talbot⁴  Manisha A. Kulkarni⁴  Heriberto Vásquez⁵  Beate Sander⁶ 

[1] ;Centro de Investigaciones en Microbiología y Parasitología Tropical (CIMPAT), Universidad de Los Andes;Grupo de Investigación en Biología Matemática y Computacional (BIOMAC), Universidad de Los Andes;School of Epidemiology and Public Health, University of Ottawa;Secretaría de Salud de Ibagué;Toronto General Hospital Research Institute, University Health Network;

关键词: Dengue;    Zika;    Chikungunya;    Aedes aegypti;    Aedes albopictus;    Colombia;   

DOI  :  10.1186/s13071-021-04908-x

来源: DOAJ

【 摘 要 】

Abstract Background Dengue, Zika and chikungunya are arboviruses of significant public health importance that are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. In Colombia, where dengue is hyperendemic, and where chikungunya and Zika were introduced in the last decade, more than half of the population lives in areas at risk. The objective of this study was to characterize Aedes spp. vectors and study their natural infection with dengue, Zika and chikungunya in Ibagué, a Colombian city and capital of the department of Tolima, with case reports of simultaneous circulation of these three arboviruses. Methods Mosquito collections were carried out monthly between June 2018 and May 2019 in neighborhoods with different levels of socioeconomic status. We used the non-parametric Friedman, Mann–Whitney and Kruskal–Wallis tests to compare mosquito density distributions. We applied logistic regression analyses to identify associations between mosquito density and absence/presence of breeding sites, and the Spearman correlation coefficient to analyze the possible relationship between climatic variables and mosquito density. Results We collected Ae. aegypti in all sampled neighborhoods and found for the first time Ae. albopictus in the city of Ibagué. A greater abundance of mosquitoes was collected in neighborhoods displaying low compared to high socioeconomic status as well as in the intradomicile compared to the peridomestic space. Female mosquitoes predominated over males, and most of the test females had fed on human blood. In total, four Ae. aegypti pools (3%) were positive for dengue virus (serotype 1) and one pool for chikungunya virus (0.8%). Interestingly, infected females were only collected in neighborhoods of low socioeconomic status, and mostly in the intradomicile space. Conclusions We confirmed the co-circulation of dengue (serotype 1) and chikungunya viruses in the Ae. aegypti population in Ibagué. However, Zika virus was not detected in any mosquito sample, 3 years after its introduction into the country. The positivity for dengue and chikungunya viruses, predominance of mosquitoes in the intradomicile space and the high proportion of females fed on humans highlight the high risk for arbovirus transmission in Ibagué, but may also provide an opportunity for establishing effective control strategies. Graphical abstract

【 授权许可】

Unknown