期刊论文详细信息
CVIR Endovascular
Image guided sclerotherapy for the treatment of venous malformations
Manraj K. S. Heran1  Jugpal S. Arneja2  Douglas J. Courtemanche2  Rebecca J. M. Courtemanche3  Steven J. Zbarsky4  Johnathon Gorman4 
[1] Department of Radiology, University of British Columbia, British Columbia Children’s Hospital;Department of Surgery, Division of Plastic Surgery, University of British Columbia, British Columbia Children’s Hospital;Department of Surgery, University of British Columbia, British Columbia Children’s Hospital;University of British Columbia;
关键词: Sclerotherapy;    Vascular malformations;    Venous malformations;    Vascular anomalies;   
DOI  :  10.1186/s42155-018-0009-1
来源: DOAJ
【 摘 要 】

Abstract Background Percutaneous sclerotherapy is the preferred method of treatment for VMs (venous malformations). However, treatment protocols vary, and research on the most effective sclerosant is conflicting. Additionally, there is limited knowledge on the effect of sclerosant volume on treatment outcome. This study aims to determine the outcomes and complications of image-guided sclerotherapy for VMs with respect to sclerosant and sclerosant volume. Towards this, a 10-year retrospective chart review was conducted of patients with VMs treated with sclerotherapy at the Vascular Anomalies Clinic at British Columbia Children’s Hospital. Results Thirty-four patients with VMs were treated of which 15 had a successful outcome, 13 had a failed outcome, and 6 had additional planned treatments after the study time period. Lesions on the head and neck or classified as type I or II had the highest success rates. Combination therapy with both ethanol and 3% STS (sodium tetradecyl sulphate), and ethanol alone had a higher success rate (64% and 60%) compared to 3% STS (11%). Major complications were most associated with 3% STS (17%) followed by ethanol (9%), and no major complications were found with combination. No relationship between the volume of sclerosant per lesion volume and outcome was found. Conclusions Combination and ethanol were the most effective sclerosants in terms of highest success rates and lowest complication rates, and sclerosant volume per lesion volume had no effect on outcomes. Future work should aim at studying larger sample sizes to account for the multiple factors that may influence the choice of sclerosant and treatment outcomes.

【 授权许可】

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