Excessive gestational weight gain in accordance with the IOM criteria and the risk of hypertensive disorders of pregnancy: a meta-analysis

BMC Pregnancy and Childbirth

Zhuoli Zhang¹  Min Ren²  Hanying Li²  Jianmin Niu³  Wenjie Ji⁴  Wei Cai⁴  Xin Zhou⁴  Yuming Li⁴  Xiulong Niu⁴ 

[1] Department of Radiology, Northwestern University Feinberg School of Medicine;Graduate School of Medicine, Tianjin Medical University;Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University;Tianjin Key Laboratory of Cardiovascular Remodeling and Target Organ Injury, Pingjin Hospital Heart Center;

关键词: Gestational weight gain;    Hypertensive disorders of pregnancy;    IOM recommendations;    Meta-analysis;   

DOI  :  10.1186/s12884-018-1922-y

来源: DOAJ

【 摘 要 】

Abstract Background Excessive gestational weight gain (GWG) is a potential risk factor for hypertensive disorders of pregnancy (HDP). Methods We systematically reviewed three electronic databases for relevant articles published in English: PubMed, EMBASE and Web of Science. The Newcastle-Ottawa Scale was used to assess study quality. Random-effects meta-analyses were performed to supply a pooled estimation of the OR comparing the risk of HDP among healthy pregnant women with and without excessive GWG. Results The pooled estimation for the association between excessive GWG and the risk of HDPs yielded an odds ratio (OR) of 1.79 (95% CI: 1.61–1.99). A subgroup analysis showed that women who had excessive GWG were more likely to have an HDP (OR 1.82; 95% CI 1.53–2.17), preeclampsia (OR 1.92; 95% CI 1.36–2.72), or gestational hypertension (OR 1.67; 95% CI 1.43–1.95). The pooled estimation for the association between excessive GWG and the risk of HDPs among pregestational normal weight women yielded an OR of 1.57 (95% CI 1.26–1.96). A subgroup analysis showed that women who had excessive GWG were more likely to have HDP (OR 1.45; 95% CI 1.09–1.92) or gestational hypertension (OR 1.51; 95% CI 1.22–1.86). The summary ORs of pre-gestational underweight women and pre-gestational overweight and obese women were 2.17 (95% CI 1.56–3.02) and 1.32 (95% CI 1.08–1.63), respectively. Conclusions The findings of this study suggest that excessive GWG in accordance with the IOM recommendations influences the rate of HDP.

【 授权许可】

Unknown