Diabetic nephropathy is ameliorated with peppermint (Mentha piperita) infusions prepared from salicylic acid-elicited plants

Journal of Functional Foods

Rosalía Reynoso-Camacho¹  Luis M. Salgado²  Marco A. Gallegos-Corona³  Iza F. Pérez-Ramírez⁴  José A. Enciso-Moreno⁵  Marely G. Figueroa-Pérez⁶ 

[1] Corresponding author at: Cerro Blanco 141, Col. Colinas del Cimatario, Querétaro, Qro. 76090, Mexico.;CICATA – Querétaro, Instituto Politécnico Nacional, Querétaro, Mexico;Facultad de Medicina, Universidad Autónoma de Querétaro, Querétaro, Mexico;Programa de Posgrado en Alimentos del Centro de la Republica (PROPAC), Centro Universitario, Universidad Autonoma de Queretaro, Mexico;Unidad de Investigación Biomédica, Instituto Mexicano del Seguro Social, Zacatecas, Mexico;Universidad Tecnológica de Culiacán, Culiacán Rosales, Sin., Mexico;

关键词: Peppermint infusions;    Elicitor;    Diabetic nephropathy;    Oxidative stress;    Inflammation;   

DOI  :  

来源: DOAJ

【 摘 要 】

Different alternatives are used to delay diabetic complications, and the functional foods have an important position due to their beneficial effects. For instance, herbal infusions are used widely to improve the health, and their favorable effects are enhanced by plant elicitation during cultivation. Peppermint (Mentha pipperita) infusions prepared from elicited plants (2 mM salicylic acid) increased their content of several compounds, principally p-hydroxybenzoic and rosmarinic acids, hesperidin, quercetin-3-O-glucoside, α-tocopherol, and β-sitosterol. The administration of these infusions decreased microalbumin and urea in urine and serum uric acid levels, and the renal accumulation of 14 inflammation-related proteins. These proteins were associated with glomerular hypertrophy, tubular damage, expansion of mesangial matrix, and cell death. The application of 2 mM SA during peppermint cultivation improved the renoprotective properties of peppermint infusions.

【 授权许可】

Unknown