Low-Intensity Pulsed Ultrasound in the Treatment of Nonunions and Fresh Fractures: A Case Series

Trauma Care

Giuseppe Toro¹  Enzo Meani²  Alexander Kirienko³  Stefania Setti⁴  Manlio Caporale⁵  Gabriele Falzarano⁶  Margareth Imbimbo⁷  Clemente Sandrone⁸  Ettore Piero Valente⁹  Carlo Luca Romanò^1,10  Antonio Toro^1,11 

[1] Department of Medical and Surgical Specialties and Dentistry, University of Campania “Luigi Vanvitelli”, 80100 Naples, Italy;Department of Osteoarticular Infections, G. Pini Orthopaedic Institute, 20122 Milan, Italy;External Fixation Unit, Humanitas Clinical and Research Center IRCCS, Via Manzoni 56, Rozzano, 20089 Milan, Italy;IGEA Clinical Biophysics, 41012 Carpi, Italy;Orthopaedics and Traumatology Complex Operative Unit, DEA ASL Roma 5, 00019 Tivoli, Italy;Orthopaedics and Traumatology Department, A.O. “G.Rummo”, 82100 Benevento, Italy;Orthopaedics and Traumatology Department, AULSS 2 Marca Trevigiana Presidi Ospedali (P.O.) of Conegliano and Vittorio Veneto, 31015 Conegliano, Italy;Osteoarticular Inflammatory Diseases Unit (MIOA), Department of Infectious Diseases and Septic Orthopaedics (MIOS), Santa Corona Hospital, 17027 Pietra Ligure (SV), Italy;Rehabilitation Department, INI Città Bianca, 03029 Veroli, Italy;Studio Medico Associato Cecca-Romanò, 20121 Milan, Italy;Unit of Orthopaedics and Traumatology, “Villa Malta” Hospital, ASL Salerno, 84087 Sarno, Italy;

关键词: low intensity pulsed ultrasound;    LIPUS;    nonunions;    fresh fractures;    healing rate;    healing time;   

DOI  :  10.3390/traumacare2020014

来源: DOAJ

【 摘 要 】

It is estimated that approximately 5% to 10% of fractures will evolve into nonunions. Nonunions have a significant impact on patient quality of life and on socioeconomic costs. Low-intensity pulsed ultrasound (LIPUS) is a non-invasive therapy widely used within the orthopedic community to accelerate the healing of fresh fractures, to minimize delayed healing, and to promote healing of nonunions. In this case series, 46 nonunions and 19 fresh fractures were treated with LIPUS for at least three months or until fracture healing. Bone healing was assessed both at a radiological and a functional level. Of the nonunions healed, 89% had a mean healing time of 89 ± 53 days. In the group of fresh fractures, the healing percentage was 95% with a mean healing time of 46 ± 28 days. LIPUS treatment is proven to be safe and well tolerated; there were no adverse events related to the use of the device, even in the presence of internal fixations and infections. LIPUS therapy should be considered a low-risk option both as an adjunct to surgery or as a standalone therapy in the management of nonunion and fresh fractures.

【 授权许可】

Unknown