Synthesis of Nitroarenes by Oxidation of Aryl Amines

Chemistry

Antonella Capperucci¹  Damiano Tanini¹ 

[1] Dipartimento di Chimica ‘Ugo Schiff’, University of Florence, Via della Lastruccia 3-13, 50019 Sesto Fiorentino (FI), Italy;

关键词: nitro compounds;    nitroarenes;    oxidation;    peroxyacids;    sodium perborate;    hydrogen peroxide;   

DOI  :  10.3390/chemistry4010007

来源: DOAJ

【 摘 要 】

Nitro compounds are an important class of organic molecules with broad application in organic synthesis, medicinal chemistry, and materials science. Among the variety of methodologies available for their synthesis, the direct oxidation of primary amines represents an attractive alternative route. Efforts towards the development of oxidative procedures for the synthesis of nitro derivatives have spanned over the past decades, leading to a wide variety of protocols for the selective oxidative conversion of amines to nitro derivatives. Methods for the synthesis of nitroarenes via oxidation of aryl amines, with particular emphasis on recent advances in the field, are summarised in this review.

【 授权许可】

Unknown