SARS-CoV-2 Rapid Antigen Testing of Symptomatic and Asymptomatic Individuals on the University of Arizona Campus

Biomedicines

Michael Badowski¹  DavidT. Harris¹  Brandon Jernigan¹  Taylor Edwards²  Ryan Sprissler²  Nirav Merchant³  Randall Cohen⁴  Stephen Paul⁴  Jarrod Mosier⁵  Kenneth Knox⁶  Catherine Spier⁷  CraigC. Weinkauf⁸  Elaine Cristan⁹  Sairam Parthasarathy⁹  Tammer El Aini⁹  Billie Bixby⁹  Christian Bime⁹  Afshin Sam⁹  Franz Rischard⁹  Madhav Chopra⁹  HeidiE. Erickson⁹  Bhupinder Natt⁹  JamesL. Knepler⁹  Sachin Chaudhary⁹  Janet Campion⁹  Michael Insel⁹  MichaelD. Dake^1,10 

[1] Biorepository, College of Medicine-Tucson, University of Arizona Health Sciences, University of Arizona, Tucson, AZ 85724, USA;College of Medicine-Tucson, University of Arizona Genetics Core, University of Arizona, Tucson, AZ 85724, USA;Data Science Institute, University of Arizona, Tucson, AZ 85724, USA;Department of Athletic, University of Arizona, Tucson, AZ 85724, USA;Department of Emergency Medicine, College of Medicine-Tucson, Tucson, AZ 85724, USA;Department of Medicine, University of Arizona-Phoenix, Phoenix, AZ 85724, USA;Department of Pathology, University of Arizona College of Medicine-Tucson, University of Arizona, Tucson, AZ 85724, USA;Department of Surgery, College of Medicine-Tucson, University of Arizona, Tucson, AZ 85724, USA;Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine-Tucson, University of Arizona, Tucson, AZ 85724, USA;Office of the Senior Vice-President for Health Sciences, University of Arizona, Tucson, AZ 85724, USA;

关键词: rapid antigen test;    PCR;    SARS-CoV-2;    asymptomatic;    diagnostic screening;   

DOI  :  10.3390/biomedicines9050539

来源: DOAJ

【 摘 要 】

SARS-CoV-2, the cause of COVID19, has caused a pandemic that has infected more than 80 M and killed more than 1.6 M persons worldwide. In the US as of December 2020, it has infected more than 32 M people while causing more than 570,000 deaths. As the pandemic persists, there has been a public demand to reopen schools and university campuses. To consider these demands, it is necessary to rapidly identify those individuals infected with the virus and isolate them so that disease transmission can be stopped. In the present study, we examined the sensitivity of the Quidel Rapid Antigen test for use in screening both symptomatic and asymptomatic individuals at the University of Arizona from June to August 2020. A total of 885 symptomatic and 1551 asymptomatic subjects were assessed by antigen testing and real-time PCR testing. The sensitivity of the test for both symptomatic and asymptomatic persons was between 82 and 90%, with some caveats.

【 授权许可】

Unknown