Radiologic screening and surveillance in hereditary cancers

European Journal of Radiology Open

Stephanie Magoon¹  Emily Jonczak²  Ty K. Subhawong²  Francesco Alessandrino³  Gina D’Amato⁴  Jamie E. Clarke⁵  Irman Forghani⁵ 

[1]Department of Radiology, Sylvester Comprehensive Cancer Center and the University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL 33136, USA

[2]Department of Hematology/Oncology, Sylvester Comprehensive Cancer Center and the University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL 33136, USA

[3]Department of Human Genetics, Miller School of Medicine, Miami, FL 33136, USA

[4]Department of Radiology, Sylvester Comprehensive Cancer Center and the University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL 33136, USA

[5]Leonard M. Miller School of Medicine, University of Miami, Miami, Florida, USA

关键词: Radiology;    Hereditary cancers;    Screening;    Surveillance;    MRI;    Whole-body MRI;   

DOI  :  

来源: DOAJ

【 摘 要 】

Hereditary cancer syndromes comprise an important subset of cancers caused by pathogenic germline mutations that can affect various organ systems. Radiologic screening and surveillance for solid tumors has emerged as a critical component of patient management in permitting early cancer detection. Although imaging surveillance may be tailored for organ-specific cancer risks, surveillance protocols frequently utilize whole-body MRI or PET/CT because of their ability to identify neoplasms in different anatomic regions in a single exam. In this review, we discuss the basic tenets of imaging screening and surveillance strategies in these syndromes, highlighting the more common neoplasms and their associated multimodality imaging findings.

【 授权许可】

Unknown