Systematic Reviews | |
Screening for depression in children and adolescents: a protocol for a systematic review update | |
Gary S. Goldfield1  Heather Bragg2  Scott Patten3  Priya Vasa4  Ainsley Moore5  John J. Riva5  Heather Colquhoun6  John C. LeBlanc7  Kathleen Pajer8  Candyce Hamel9  Beverley J. Shea9  Becky Skidmore9  David Moher9  Brian Hutton9  Andrew Beck9  Adrienne Stevens9  Brett D. Thombs1,10  Stuart Gordon Nicholls1,11  Eva Graham1,12  Kate Morissette1,12  Ian Colman1,13  Beth K. Potter1,13  Julian Little1,13  Eddy Lang1,14  Robert Meeder1,15  | |
[1] Children’s Hospital of Eastern Ontario Research Institute;Children’s Hospital of Eastern Ontario;Department of Community Health Services and Department of Psychiatry, University of Calgary;Department of Family and Community Medicine, St. Michael’s Hospital, University of Toronto;Department of Health Research Methods, Evidence and Impact, McMaster University;Department of Occupational Science and Occupational Therapy, University of Toronto;Department of Pediatrics, Dalhousie University;Department of Psychiatry, Children’s Hospital of Eastern Ontario, Ottawa Faculty of Medicine;Knowledge Synthesis Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Centre for Practice-Changing Research;Lady Davis Institute of the Jewish General Hospital;Ottawa Hospital Research Institute;Public Health Agency of Canada;School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa;University of Calgary Cumming School of Medicine;Waypoint Centre For Mental Health Care; | |
关键词: Depression; screening; systematic review; child; children; adolescent; | |
DOI : 10.1186/s13643-020-01568-3 | |
来源: DOAJ |
【 摘 要 】
Abstract Background Major depressive disorder is common, debilitating, and affects feelings, thoughts, mood, and behaviors. Childhood and adolescence are critical periods for the development of depression and adolescence is marked by an increased incidence of mental health disorders. This protocol outlines the planned scope and methods for a systematic review update that will evaluate the benefits and harms of screening for depression in children and adolescents. Methods This review will update a previously published systematic review by Roseman and colleagues. Eligible studies are randomized controlled trials (RCTs) assessing formal screening in primary care to identify children or adolescents not already self-reporting symptoms of, diagnosed with, or treated for depression. If no or only a single RCT is available, we will consider controlled studies without random assignment. Studies of participants with characteristics associated with an elevated risk of depression will be analyzed separately. Outcomes of interest are symptoms of depression, classification of major depressive disorder based on a validated diagnostic interview, suicidality, health-related quality of life, social function, impact on lifestyle behavior (e.g., substance use, school performance, lost time at work, or school), false-positive results, overdiagnosis, overtreatment, labeling, and other harms such as those arising from treatment. We will search MEDLINE, Embase, PsycINFO, CINAHL, the Cochrane Library, and grey literature sources. Two reviewers will independently screen the titles and abstracts using the liberal accelerated method. Full-text screening will be performed independently by two reviewers using pre-specified eligibility criteria. Data extraction and risk of bias assessments will be performed independently by two reviewers. Pre-planned analyses, including subgroup and sensitivity analyses, are detailed within this protocol. Two independent reviewers will assess and finalize through consensus the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, and prepare GRADE evidence profiles and summary of findings tables for each outcome of interest. Discussion The systematic review will provide a current state of the evidence of benefits and harms of depression screening in children and adolescents. These findings will be used by the Canadian Task Force on Preventive Health Care to inform the development of recommendations on depression screening. Systematic review registration PROSPERO CRD42020150373
【 授权许可】
Unknown