Efficacy of graphene nanosheets on the plasma sprayed hydroxyapatite coating: Improved strength, toughness and in-vitro bioperformance with osteoblast

Materials & Design

Shaokang Guan¹  Jia Ren²  Yufeng Sun³  Weiwei Liu⁴  Xiaolong Lu⁵  Yao Chen⁶ 

[1] Electric Engineering, Soochow University, Suzhou 215006, China;Key Laboratory of Advanced Magnesium Alloys in Henan Province, Zhengzhou University, Zhengzhou 450002, China;;Key Laboratory of Advanced Materials Processing &Mold, Ministry of Education, Zhengzhou 450002, China;;School of Mechanical &School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China;

关键词: Ceramic-matrix composites;    Plasma spray;    Mechanical properties;    Graphene nanosheet;    Hydroxyapatite;    In-vitro biocompatibility;   

DOI  :  

来源: DOAJ

【 摘 要 】

Graphene nanosheet (GNS) reinforced HA coating on Ti6Al4V substrate, fabricated using plasma spray, was developed for biomedical applications. Microstructural observation corroborated that the adding GNSs homogeneously distributed in the GNS/HA coating with typical lamellar structure featured by GNSs acting as binder between the discrete HA splats. Meanwhile, GNSs were observed to get in direct contact with HA matrix and form a clean GNS-HA interface without interfacial product. Results of various indentation tests showed simultaneous improvement in both indentation yield strength (~379 MPa) and fracture toughness (0.78 ± 0.17 MPam1/2), mainly attributing to synergetic toughening and strengthening mechanisms associated with the adding GNSs such as load transfer, GNS pull-out, inter-layer sliding of a GNS, crack branching, GNS bridging and crack deflection. In addition, the GNS/HA coating exhibited improved biocompatible with MG-63 cell in terms of its attachment, adhesion strength, proliferation and differentiation. Hence, the GNS/HA composite coating with improved strength, toughness and enhanced biocompatibility makes it a promising candidate for bone regeneration and implantation.

【 授权许可】

Unknown