POSS Hybrid Robust Biomass IPN Hydrogels with Temperature Responsiveness

Polymers

Guangsheng Zeng¹  Wenyong Liu¹  Yueyun Zhou²  Yi Chen²  Hejie Pi² 

[1] Hunan Provincial Engineering Laboratory of Key Technique of Non-metallic Packaging Waste Resources Utilization, Hunan University of Technology, Zhuzhou 412007, China;Hunan Provincial Key Laboratory of Comprehensive Utilization of Agricultural and Animal Husbandry Waste Resources, College of Urban and Environmental Sciences, Hunan University of Technology, Zhuzhou 412007, China;

关键词: octa-ammonium POSS;    sodium alginate;    hydrogels;    temperature responsiveness;   

DOI  :  10.3390/polym11030524

来源: DOAJ

【 摘 要 】

In order to improve the performance of traditional sodium alginate (SA) hydrogels cross-linked by Ca²⁺ ions to meet greater application demand, a strategy was designed to structure novel SA-based gels (named OP-PN gels) to achieve both stimulus responsiveness and improved mechanical strength. In this strategy, the SA chains are co-cross-linked by CaCl₂ and cationic octa-ammonium polyhedral oligomeric silsesquioxane (Oa-POSS) particles as the first network, and an organically cross-linked poly(N-isopropyl acrylamide) (PNIPA) network is introduced into the gels as the second network. Several main results are obtained from the synthesis and characterization of the gels. For OP-PN gels, their properties depend on the content of both uniformly dispersed Oa-POSS and PNIPA network directly. The increased Oa-POSS and PNIPA network content significantly improves both the strength and resilience of gels. Relatively, the increased Oa-POSS is greatly beneficial to the modulus of gels, and the increased PNIPA network is more favorable to advancing the tensile deformation of gels. The gels with hydrophilic PNIPA network exhibit better swelling ability and remarkable temperature responsiveness, and their volume phase transition temperature can be adjusted by altering the content of Oa-POSS. The deswelling rate of gels increases gradually with the increase of POSS content due to the hydrophobic Si–O skeleton of POSS. Moreover, the enhanced drug loading and sustained release ability of the target drug bovine serum albumin displays great potential for this hybrid gel in the biomedical field.

【 授权许可】

Unknown