Clinical and immunological efficacy of immunoprophylaxis of influenza in children with allergic diseases

Медицинский совет

N. E. Tkachenko¹  F. C. Shakhtakhtinskaya¹  A. G. Gaivoronskaya¹  M. I. Broeva²  L. S. Namazova-baranova³  M. V. Fedoseenko³  E. G. Bokuchava³  T. A. Kalyuzhnaya³  D. A. Novikova³ 

[1] First Moscow State Medical University named after I.M. Sechenov;Russian National Research Medical University named after N.I. named after N.I. Pirogov;Research Center of Children's Health;

关键词: противогриппозные вакцины;    аллергические болезни;    вакцинопрофилактика гриппа;    острые респираторные инфекции;    грипп;    flu vaccines;    allergic diseases;    vaccine prophylaxis of influenza;    acute respiratory infections;    flu;   

DOI  :  10.21518/2079-701X-2016-1-118-122

来源: DOAJ

【 摘 要 】

Despite the fact that according to the guidelines of the World Health Organization all patients with allergic disorders should be annually vaccinated against influenza, regardless of the form or severity of the disease and ongoing drug therapy, that is still not applicable in practice. This fact entails at least two negative outcomes: the risk of infectious disease and its complications, as well as increased likelihood of exacerbation of the allergic disease against a background of the intercurrent infection. The aim of the study was to investigate the effectiveness and tolerability of domestic and foreign vaccines against the flu in children with allergic diseases. The study demonstrated good tolerability of the researched vaccines, absence of evident local and/or systemic reactions and of exacerbations of allergic diseases. The study found that vaccination completely protects children from the flu and significantly reduces the incidence of ARI, leading to an increase in the remission period and lower incidence of exacerbations of the underlying disease.

【 授权许可】

Unknown