Sinonasal ameloblastoma: A case report focusing on histogenesis and related morphological characteristics

Oral and Maxillofacial Surgery Cases

Sotai Kimura, DDS, MD, PhD¹  Hiroshi Harada, DDS, PhD²  Akira Kurose, MD, PhD³  Koichi Higaki, MD, PhD³  Yoshizo Kimura, MD, PhD⁴ 

[1] Corresponding author. Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, 5 Zaifu, Hirosaki, 036-8562, Japan.;Department of Anatomic Pathology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan;Department of Diagnostic Pathology, St. Mary's Hospital, Kurume, Japan;Department of Molecular Pathology, Yamaguchi University Graduate School of Medicine, Ube, Japan;

关键词: Ameloblastoma;    Odontogenic tumor;    Sinonasal tract;    Jawbone;    Histogenesis;   

DOI  :  

来源: DOAJ

【 摘 要 】

Sinonasal ameloblastoma is an extremely rare neoplasm. Herein we present a case of sinonasal ameloblastoma and discuss its histogenesis and related morphological characteristics. An 80 years-old Japanese male had a polypoid mass initially diagnosed as a nasal polyp. A prior biopsy was interpreted as a salivary gland-type tumor and he was therefore referred to a regional general hospital for surgical removal of the lesion. Preoperative contrast-enhanced magnetic resonance imaging revealed a space-occupying lesion in the right nasal cavity and the right maxillary sinus with poor contrast enhancement. Histopathological findings revealed that the tumor consisted of follicular/plexiform-like cell nests with peripheral palisading, extending continuously to the adjacent mucosa. A recurrent polypoid mass accompanied by bone destruction of the maxillary sinus was found two years after the surgery, but it was left untreated. Although sinonasal ameloblastoma remains under-recognized, its characteristics, including its histopathological features, need to be more widely known to allow its correct diagnosis and adequate management.

【 授权许可】

Unknown