Depression and anxiety in different hypertension phenotypes: a cross-sectional study

Annals of General Psychiatry

János Nemcsik¹  Helga Gyöngyösi¹  Beáta Kőrösi¹  Dóra Batta¹  Péter Torzsa¹  Zsófia Nemcsik-Bencze²  Illés Kovács³  Zoltán Rihmer⁴  Xénia Gonda⁴  Andrea László⁵ 

[1]Department of Family Medicine, Semmelweis University

[2]Department of Neuroradiology, Semmelweis University

[3]Department of Ophthalmology, Semmelweis University

[4]Department of Psychiatry and Psychotherapy, Semmelweis University

[5]Norisana – MVZ Rosenau

关键词: Depression;    Anxiety;    Resistant hypertension;    White-coat hypertension;   

DOI  :  10.1186/s12991-022-00400-7

来源: DOAJ

【 摘 要 】

Abstract Background Hypertension is a major risk factor of cardiovascular mortality. Mood disorders represent a growing public health problem worldwide. A complex relationship is present between mood disorders and cardiovascular diseases. However, less data is available about the level of depression and anxiety in different hypertension phenotypes. The aim of our study was to evaluate psychometric parameters in healthy controls (Cont), in patients with white-coat hypertension (WhHT), with chronic, non-resistant hypertension (non-ResHT), and with chronic, treatment-resistant hypertension (ResHT). Methods In a cross-sectional study setup 363 patients were included with the following distribution: 82 Cont, 44 WhHT, 200 non-ResHT and 37 ResHT. The patients completed the Beck Depression Inventory (BDI) and the Hamilton Anxiety Scale (HAM-A). Results BDI points were higher in WhHT (7 (3–11)) and ResHT (6 (3–11.5)) compared with Cont (3 (1–6), p < 0.05). Similarly, HAM-A points were higher in WhHT (8 (5–15)) and ResHT (10.5 (5.25–18.75)) compared with Cont (4 (1–7), p < 0.05) and also compared with non-ResHT (5 (2–10), p < 0.05). ResHT was independently associated with HAM-A scale equal or above 3 points (Beta = 3.804, 95%CI 1.204–12.015). WhHT was independently associated with HAM-A scale equal or above 2 points (Beta = 7.701, 95%CI 1.165–18.973) and BDI scale equal or above 5 points (Beta = 2.888, 95%CI 1.170–7.126). Conclusions Our results suggest psychopathological similarities between white-coat hypertension and resistant hypertension. As recently it was demonstrated that white-coat hypertension is not a benign condition, our findings can have relevance for future interventional purposes to improve the outcome of these patients.

【 授权许可】

Unknown