Influence of Visual and Vestibular Hypersensitivity on Derealization and Depersonalization in Chronic Dizziness

Frontiers in Neurology

Sylvie Heuschen¹  Anne Cassoulet¹  Ulla Duquesne²  Christian Van Nechel²  Michel Toupet³  Alexis Bozorg Grayeli⁴  Charlotte Hautefort⁶ 

[1] Centre d'Explorations Fonctionnelles Otoneurologiques, Paris, France;Clinique des Vertiges, Brussels, Belgium;Institut de Recherche Oto-Neurologique (IRON), Paris, France;Le2i, Electronic, Image and Computer Research Laboratory, Dijon, France;Otolaryngology Department, Dijon University Hospital, Université Bourgogne-Franche Comté, Dijon, France;Otolaryngology Department, Hôpital Lariboisière, APHP, Paris, France;

关键词: chronic vertigo;    persistent postural-perceptual dizziness;    migraine;    optic flow vertigo;    motion sickness;    anxiety;   

DOI  :  10.3389/fneur.2019.00069

来源: DOAJ

【 摘 要 】

Objective: The aim of this study was to investigate the relation between visual and vestibular hypersensitivity, and Depersonalization/Derealization symptoms in patients with chronic dizziness.Materials and Methods: 319 adult patients with chronic dizziness for more than 3 months (214 females and 105 males, mean age: 58 years, range: 13–90) were included in this prospective cross-sectional study. Patients underwent a complete audio-vestibular workup and 3 auto questionnaires: Hospital Anxiety and Depression (HAD), Depersonalization/Derealization Inventory (DDI), and an in-house questionnaire (Dizziness in Daily Activity, DDA) assessing 9 activities with a score ranging from 0 (no difficulty) to 10 (maximal discomfort) and 11 (avoidance) to detect patients with visual and vestibular hypersensitivity (VVH, a score > 41 corresponding to mean + 1 standard deviation).Results: DDI scores were higher in case of VVH (6.9 ± 6.79, n = 55 vs. 4.2 ± 4.81, n = 256 without VVH, p < 0.001, unpaired t-test), migraine (6.1 ± 6.40, n = 110 vs. 4.0 ± 4.42, n = 208no migraine, p < 0.001, unpaired t-test), and motion sickness (6.8 ± 5.93, n = 41 vs. 4.4 ± 5.11, n = 277 no motion sickness, p < 0.01, unpaired t-test). Women scored DDI higher than men (5.1 ± 5.42, n = 213 vs. 3.9 ± 4.91, n = 105, respectively, p < 0.05, unpaired t-test). DDI scores were also related to depression and anxiety. DDI score was also higher during spells than during the basal state.Conclusion: During chronic dizziness, Depersonalization/Derealization symptoms seem to be related to anxiety and depression. Moreover, they were prominent in women, in those with visual and vestibular hypersensitivity, migraine, and motion sickness.

【 授权许可】

Unknown