Multimodal Locomotion and Active Targeted Thermal Control of Magnetic Agents for Biomedical Applications

Advanced Science

So‐Jung Gwak¹  Sung Hoon Kim²  Armando Ramos‐Sebastian² 

[1] Department of Chemical Engineering Wonkwang University Iksan 54538 Republic of Korea;Department of Electronics Convergence Engineering Wonkwang University Iksan 54538 Republic of Korea;

关键词: electromagnetic system;    magnetic hyperthermia;    magnetic microrobots;    magnetic nanoparticles;   

DOI  :  10.1002/advs.202103863

来源: DOAJ

【 摘 要 】

Abstract Magnetic microrobots can be miniaturized to a nanometric scale owing to their wireless actuation, thereby rendering them ideal for numerous biomedical applications. As a result, nowadays, there exist several mechano‐electromagnetic systems for their actuation. However, magnetic actuation is not sufficient for implementation in biomedical applications, and further functionalities such as imaging and heating are required. This study proposes a multimodal electromagnetic system comprised of three pairs of Helmholtz coils, a pair of Maxwell coils, and a high‐frequency solenoid to realize multimodal locomotion and heating control of magnetic microrobots. The system produces different configurations of magnetic fields that can generate magnetic forces and torques for the multimodal locomotion of magnetic microrobots, as well as generate magnetic traps that can control the locomotion of magnetic swarms. Furthermore, these magnetic fields are employed to control the magnetization of magnetic nanoparticles, affecting their magnetic relaxation mechanisms and diminishing their thermal properties. Thus, the system enables the control of the temperature increase of soft‐magnetic materials and selective heating of magnetic microrobots at different positions, while suppressing the heating properties of magnetic nanoparticles located at undesired areas.

【 授权许可】

Unknown