Prevalence of Alzheimer dementia in Upper Egypt (desert areas)

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Ghaydaa A. Shehata¹  Tarek A. Rageh¹  Hamdy N. A. EL Tallawy¹  Mostafa K. Ghanem¹  Mohamed Abd El Hamed¹  Ahmed H. Yousef¹  Wafaa M. A. Farghaly¹  Khaled Usama¹  Reda Badry¹  Amal M. Tohamy¹  Khaled O. Abdulghani²  Mohamed A. Sayed³  Heba S. Hashem⁴ 

[1] Department of Neurology and Psychiatry, Assuit University;Department of Neurology and Psychiatry, Helwan University School of Medicine;Department of Neurology and Psychiatry, Sohag University;National institute of Research;

关键词: Prevalence;    Alzheimer’s dementia;    Desert;    Egypt;   

DOI  :  10.1186/s41983-019-0074-y

来源: DOAJ

【 摘 要 】

Abstract Background Alzheimer’s disease (AD) is the commonest type of Dementia worldwide. It rapidly increases with aging especially over 70 years. Objectives The aims of this study are to determine the prevalence of AD in Egyptian desert areas and to identify the risk factors and presenting symptoms. Methods This study was carried out on desert areas Al Kharga district and Al Quseir city. All population aged 50 years and more (12,508) were included through door to door survey by seven Neuropsychiatrists. They were screened by standardized questionnaire prepared specifically. Positive cases were invited to attend Assiut Univ. Hospital where clinical evaluation, according to DSM-IV R. and necessary psychometric tests were applied. Results One hundred twenty-six patients with AD were diagnosed out of 12,508 people aged 50 years; yielding a prevalence of 1%. Prevalence increases with age, from 0.34% for those aged 60 ≤ 70 years to 2.9% for subjects aged 70 ≤ 80 years, and 9.74% for those aged 80 years and more. AD is more common among females than males in all ages. Eighty-five percent of diagnosed patients are of mild and moderate degrees. Hypertension (14.3%), smoking (10.3%), diabetes (8.73%), prior epilepsy (5.6%), and family history of AD (3.5%) are common risk factors. Impaired self-care (88.1%), memory loss (84.1%), impaired social judgment (77%), agnosia (58.7%), and behavioral changes (48.4%) are the most frequently encountered symptoms of AD. Conclusion Prevalence of AD was 1% for population aged 50 years and more, reaching 9.7 for patients aged > 80 years. Early onset AD (< 65 years) was recorded in 7.9%.

【 授权许可】

Unknown