Multimodality Imaging in the Diagnosis of Prosthetic Valve Endocarditis: A Brief Review

Frontiers in Cardiovascular Medicine

Krishna Upadhyaya¹  Jakob Park²  Lissa Sugeng³  David J. Hur³  Bryan D. Young³  Maxwell D. Eder³  Maricar Malinis⁴  Matthew Ringer⁴ 

[1] Ascension Medical Group, Section of Cardiovascular Medicine, Milwaukee, WI, United States;Department of Internal Medicine, Yale New Haven Hospital, New Haven, CT, United States;Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, United States;Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States;

关键词: prosthetic;    valve;    endocarditis (infectious);    multimodality;    imaging;    endocarditis team;   

DOI  :  10.3389/fcvm.2021.750573

来源: DOAJ

【 摘 要 】

Infective endocarditis is a common and treatable condition that carries a high mortality rate. Currently the workup of infective endocarditis relies on the integration of clinical, microbiological and echocardiographic data through the use of the modified Duke criteria (MDC). However, in cases of prosthetic valve endocarditis (PVE) echocardiography can be normal or non-diagnostic in a high proportion of cases leading to decreased sensitivity for the MDC. Evolving multimodality imaging techniques including leukocyte scintigraphy (white blood cell imaging), 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), multidetector computed tomographic angiography (MDCTA), and cardiac magnetic resonance imaging (CMRI) may each augment the standard workup of PVE and increase diagnostic accuracy. While further studies are necessary to clarify the ideal role for each of these imaging techniques, nevertheless, these modalities hold promise in determining the diagnosis, prognosis, and care of PVE. We start by presenting a clinical vignette, then evidence supporting various modality strategies, balanced by limitations, and review of formal guidelines, when available. The article ends with the authors' summary of future directions and case conclusion.

【 授权许可】

Unknown