Design and synthesis of polycyclic sulfones via Diels–Alder reaction and ring-rearrangement metathesis as key steps

Beilstein Journal of Organic Chemistry

Rama Gunta¹  Sambasivarao Kotha¹ 

[1] Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai-400 076, India, Fax: [phone];

关键词: alkenylation;    Diels–Alder reaction;    ring-rearrangement metathesis;    sulfones;   

DOI  :  10.3762/bjoc.11.148

来源: DOAJ

【 摘 要 】

Here, we describe a new and simple synthetic strategy to various polycyclic sulfones via Diels–Alder reaction and ring-rearrangement metathesis (RRM) as the key steps. This approach delivers tri- and tetracyclic sulfones with six (n = 1), seven (n = 2) or eight-membered (n = 3) fused-ring systems containing trans-ring junctions unlike the conventional all cis-ring junctions generally obtained during the RRM sequence. Interestingly the starting materials used are simple and commercially available.

【 授权许可】

Unknown