Quality of Life, Postoperative Pain, and Lymph Node Dissection in a Robotic Approach Compared to VATS and OPEN for Early Stage Lung Cancer

Journal of Clinical Medicine

Patrick Maisonneuve¹  Giulia Veronesi²  Elisa Dieci²  Pierluigi Novellis²  Alberto Testori³  Edoardo Bottoni³  Umberto Cariboni³  Emanuele Voulaz³  Marco Alloisio³  Sara Di Stefano³  Michela Solinas⁴ 

[1] Division of Epidemiology and Biostatistics, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy;Division of Thoracic Surgery, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy;Humanitas Clinical and Research Center, Division of Thoracic and General Surgery, Rozzano, 20089 Milan, Italy;Thoracic Surgery Unit, New Hospital of Legnano, ASST Ovest, 20025 Milan, Italy;

关键词: robotic surgery;    lung cancer;    early stage;    quality of life;    postoperative pain;   

DOI  :  10.3390/jcm10081687

来源: DOAJ

【 摘 要 】

We compare the perioperative course, postoperative pain, and quality-of-life (QOL) in patients undergoing anatomic resections of early-stage lung cancer by means of robotic surgery (RATS), video-assisted thoracic surgery (VATS), or muscle-sparing thoracotomy (OPEN); 169 consecutive patients with known/suspected lung cancer, candidates to anatomic resection, were enrolled in a single-center prospective study from April 2016 to December 2018. EORTC QLQ-C30 and QLQ-LC13 scores were obtained preoperatively and, at three time points, postoperatively. RATS and VATS groups were matched for ASA scores, while RATS and open surgery were matched for gender, ASA score, cancer stage, and tumor size; 58 patients underwent open surgery, 58 had VATS, and 53 had RATS. Hospital stay was shorter after RATS than OPEN (median 4.5 versus 5; p = 0.047). Comparing matched RATS and VATS groups, the number of hilar lymph nodes and nodal stations removed was significantly higher in the former approach (p = 0.01 vs. p < 0.0001); conversely, pain at 2 weeks was slightly lower after VATS (p = 0.004). No significant difference was observed in conversions, complications, duration of surgery, and postoperative hospitalization. The robotic approach was superior to OPEN in terms of QOL, pain, and length of postoperative stay and showed improved lymph node dissection compared to VATS.

【 授权许可】

Unknown