Ameloblastoma with distinctive granular cell pattern

Autopsy and Case Reports

Silvia Vanessa Lourenço¹  Cláudia Malheiros Coutinho Camillo²  Clóvis Antônio Lopes Pinto²  Ana Maria Hoyos Cadavid³  Tathyane Harumi Nakajima Teshima³ 

[1] ;AC Camargo Cancer Center;Universidade de São Paulo, School of Dentistry;

关键词: Ameloblastoma;    Odontogenic Tumors;    Neoplasms;   

DOI  :  

来源: DOAJ

【 摘 要 】

Ameloblastoma with granular cell pattern (AGC) is classified as an unusual histological subtype of solid/multicystic ameloblastoma, characterized by granular changes in stellate-like cells located within the inner portion of the epithelial follicles. Studies have revealed that lysosomal overload causes cytoplasmic granularity; however, the mechanism involved remains poorly understood. Here we report on eight cases of granular cell ameloblastoma, in the posterior region of the mandible. The age of the patients included in this case series ranged from 35 -64 years old and 87.5% of cases occurred in non-Caucasians, with a slight gender predilection for men (62.5%). There was no evidence of recurrence, and the majority of the cases were treated with surgical resection (87.5%). All tumors displayed histopathological features consistent with the diagnosis of ameloblastoma with granular cell pattern.

【 授权许可】

Unknown