New Emergence of the Novel Pestivirus Linda Virus in a Pig Farm in Carinthia, Austria

Viruses

Sandra Högler¹  René Brunthaler¹  Marianne Zaruba²  Alexandra Kiesler²  Katharina Dimmel²  Kerstin Seitz²  Marlene Mötz²  Till Rümenapf²  Angelika Auer²  Christiane Riedel²  Benjamin Lamp³  Andrea Ladinig⁴  Lukas Schwarz⁴ 

[1] Department for Pathobiology, Institute of Pathology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria;Department for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria;Faculty of Veterinary Medicine, Institute of Virology, Justus-Liebig-University Giessen, Schubertstrasse 81, 35392 Giessen, Germany;University Clinic for Swine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria;

关键词: emerging disease;    Flaviviridae;    pestivirus;    atypical porcine pestivirus;    Bungowannah virus;    congenital tremor;   

DOI  :  10.3390/v14020326

来源: DOAJ

【 摘 要 】

Linda virus (LindaV) was first identified in a pig farm in Styria, Austria in 2015 and associated with congenital tremor (CT) type A-II in newborn piglets. Since then, only one more LindaV affected farm was retrospectively discovered 10 km away from the initially affected farm. Here, we report the recent outbreak of a novel LindaV strain in a farrow-to-finish farm in the federal state Carinthia, Austria. No connection between this farm and the previously affected farms could be discovered. The outbreak was characterized by severe CT cases in several litters and high preweaning mortality. A herd visit two months after the onset of clinical symptoms followed by a diagnostic workup revealed the presence of several viremic six-week-old nursery pigs. These animals shed large amounts of virus via feces and saliva, implying an important epidemiological role for within- and between-herd virus transmission. The novel LindaV strain was isolated and genetically characterized. The findings underline a low prevalence of LindaV in the Austrian pig population and highlight the threat when introduced into a pig herd. Furthermore, the results urge the need to better understand the routes of persistence and transmission of this enigmatic pestivirus in the pig population.

【 授权许可】

Unknown