Synthesis and Characterization of Low Molecular Weight Chitosan

BioResources

Yihui Yin¹  Liyan Xing¹  Wei Jiang²  Xue Zheng²  Junwen Pu² 

[1] China;MOE Engineering Research Center of Forestry Biomass Materials and Bioenergy, Beijing Forestry University, Beijing, 100083, PR China;

关键词: Chitosan;    Low molecular weight;    Sodium hypochlorite;    Box-Behnken design;   

DOI  :  10.15376/biores.10.2.2338-2349

来源: DOAJ

【 摘 要 】

Chitosan can be widely used in many areas owing to its unique properties, although its poor solubility in water is still a limiting factor. In the present study, low molecular weight chitosan (LMWC) was prepared by degradation with NaClO so that chitosan was able to dissolve in water. Chitosan to liquor ratio, NaClO content, temperature, and time were considered variables of NaClO degradation, and the Box-Behnken design was used to determine optimal conditions. There was good agreement between the experimental data and their predicted counterparts. The optimum conditions for chitosan degradation were estimated to be 1:67.91 of chitosan to liquor ratio, 22.03% of NaClO content, a temperature of 90.3 °C, and a time of 3.07 h. It was found that synthesis under these optimized conditions achieved the lowest molecular weight (10,937.4 Daltons). In addition, Fourier transform infrared spectroscopy, X-ray diffractograms, and thermogravimetric analysis showed that the structure of LMWC was similar to the original chitosan, while the crystallinity and thermal stability decreased after degradation.

【 授权许可】

Unknown