Auditory brainstem responses in term newborns with hyperbilirubinemia

Einstein (São Paulo)

关键词: Infant;    newborn;    Jaundice;    Hyperbilirubinemia;    Evoked potentials;    auditory;    Hearing tests;    Kernicterus;   

DOI  :  

来源: DOAJ

【 摘 要 】

Objective: To evaluate auditory brainstem responses in term newbornswith hyperbilirubinemia. Methods: Seventy-one newborns, 35 withaggravated physiological neonatal jaundice (group I), 24 with ABOblood incompatibility (group II) and 12 not suffering from jaundice orany other disease were submitted to auditory brainstem responses.Statistical analysis of variance was performed to evaluate waveformreproducibility, absolute and interwave latencies, and Pearsoncoefficient was used to evaluate the association between the level ofserum bilirubin and abnormalities in the auditory brainstem responses.Results: According to the criteria assumed in the present paperwaveform alterations were more frequently found in group II than inthe control group (p = 0.023). No significant differences were observedbetween groups I and II (p = 0.083) or between control group andgroup I (p = 0.166). Wave I latency at 80 dBHL for good reproducibilityresponses and III-V interwave latency at 40 dBHL for poor reproducibilityresponses of newborns with hyperbilirubinemia showed significantfindings in relation to the control group (0.008 and 0.004 respectively).There was positive, weak (9%) association between serum indirectbilirubin levels and auditory brainstem responses only when the twogroups were analyzed together. Conclusions: Neonatalhyperbilirubinemia changed the conduction of auditory stimulus interm newborns with jaundice caused by ABO blood incompatibility.There was poor positive association between plasma levels of bilirubinand abnormalities in auditory brainstem responses.

【 授权许可】

Unknown