Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines

Beilstein Journal of Organic Chemistry

Wesley J. Moran¹  Somaia Kamouka¹ 

[1] Department of Chemistry, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK. Tel: [phone];

关键词: amides;    catalysis;    cyclization;    hypervalent iodine;    isoxazolines;   

DOI  :  10.3762/bjoc.13.177

来源: DOAJ

【 摘 要 】

Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.

【 授权许可】

Unknown