Cerebellar Coordination of Neuronal Communication in Cerebral Cortex

Frontiers in Systems Neuroscience

Roy V. Sillitoe¹  Yu Liu²  Samuel S. McAfee³  Detlef H. Heck⁷ 

[1] Therapeutics Graduate Program, Baylor College of Medicine, Houston, TX, United States;Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN, United States;Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, TN, United States;Department of Neuroscience, Baylor College of Medicine, Houston, TX, United States;Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States;;Development, Disease Models &Jan and Dan Duncan Neurological Research Institute of Texas Children’s Hospital, Houston, TX, United States;

关键词: cerebellum;    cerebrocerebellar communication;    coherence;    functional connectivity;    cognition;   

DOI  :  10.3389/fnsys.2021.781527

来源: DOAJ

【 摘 要 】

Cognitive processes involve precisely coordinated neuronal communications between multiple cerebral cortical structures in a task specific manner. Rich new evidence now implicates the cerebellum in cognitive functions. There is general agreement that cerebellar cognitive function involves interactions between the cerebellum and cerebral cortical association areas. Traditional views assume reciprocal interactions between one cerebellar and one cerebral cortical site, via closed-loop connections. We offer evidence supporting a new perspective that assigns the cerebellum the role of a coordinator of communication. We propose that the cerebellum participates in cognitive function by modulating the coherence of neuronal oscillations to optimize communications between multiple cortical structures in a task specific manner.

【 授权许可】

Unknown