Fibrous dysplasia of the clivus – A case study and literature review

Radiology Case Reports

Kunj Patel, MBBS, BSc (Hons)¹  Aqeel Butt, MBBS, BSc (Hons)²  Kanupriya Agrawal, MBBS³  Alok Arya, MBBS³  Jaswinder Singh, MBBS³ 

[1] Corresponding author.;London North West University Healthcare NHS Trust, Ealing Hospital, Uxbridge Road, Southall UB1 3HW, United Kingdom;Radiology Department, Watford General Hospital, Vicarage Road, Watford WD18 0HB, United Kingdom;

关键词: Clivus;    Fibrous dysplasia;    Clival fibrous dysplasia;    Ground-glass;   

DOI  :  

来源: DOAJ

【 摘 要 】

Fibrous dysplasia is a benign, congenital skeletal disorder which leads to the formation of fibro-osseous intramedullary bone lesions. Clival fibrous dysplasia is a rare variant which commonly presents asymptomatically with no findings on examination and is often picked up incidentally on radiological investigation. A 39-year-old female presented with a sudden onset headache of 3 days’ duration alongside diplopia and right lower limb weakness upon examination. Computerized tomography head scan revealed an expansile clivus with a ground-glass appearance, magnetic resonance imaging brain scan revealed a predominantly hypointense signal on T1- and T2-weighted images and subsequent whole-body bone imaging confirmed the diagnosis of monostotic clival fibrous dysplasia. This case highlights the importance of considering monostotic clival fibrous dysplasia as a differential diagnosis in patients presenting with sudden onset symptoms of headache alongside cranial and peripheral nerve involvement, when other more sinister causes have been excluded.

【 授权许可】

Unknown