Short and Concise Peer-to-Peer Teaching—Example of a Successful Antibiotic Stewardship Intervention to Increase Iv to Po Conversion

Antibiotics

Thomas Münzel¹  Johannes Wild¹  Ingo Sagoschen¹  Lukas Hobohm¹  Bettina Siegrist²  Thomas Schwanz³ 

[1] Department of Cardiology, Cardiology I, University Medical Center Mainz, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany;Department of Pharmacy, University Medical Center Mainz, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany;Institute of Medical Microbiology and Hygiene, University Medical Center Mainz, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany;

关键词: antibiotic stewardship;    defined daily doses;    antibiotic prescribing;    antibiotic use;    peer-to-peer teaching;   

DOI  :  10.3390/antibiotics11030402

来源: DOAJ

【 摘 要 】

Antibiotic stewardship (ABS) programs aim to combine effective treatment with minimized antibiotic-related harms. Common ABS interventions are simple and effective, but their implementation in daily practice is often difficult. The aim of our study was to investigate if a single, short, peer-to-peer teaching intervention (junior doctor to junior doctor) during clinical routine can successfully improve antibiotic prescriptions. We performed a quasi-experimental before–after study on a regular care cardiology ward at a large academic medical center in Germany. We evaluated antibiotic use metrics retrospectively and calculated defined daily doses (DDD) with the anatomical therapeutic chemical/DDD classification system of the World Health Organization. We hypothesize that the over-representative use of intravenous administration is a potentially modifiable target, which can be proven by antibiotic use metrics analysis. After a single peer-to-peer teaching session with a focus on indications for iv to po conversion, the normalized percentage of intravenous compared to oral administration significantly decreased (from 86.5 ± 50.3% to 41.4 ± 70.3%). Moreover, after the intervention, antibiotics with high oral bioavailability were no longer administered intravenously at all during the following quarter. Our results indicate that even a single peer-to-peer training session is highly effective in improving the iv to po conversion rate in the short term.

【 授权许可】

Unknown