Fiber Optic Sensor for Real-time Monitoring of Freezing–Thawing Cycle in Cryosurgery

Applied Sciences

Nikolaos Kourkoumelis¹  Aris Ikiades²  Thomas Dalagiannis³  Dimosthenis Spasopoulos³  Archontis Kaisas³  George Rattas³  IoannisD. Bassukas⁴ 

[1] Venereal Diseases, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece;Department of Medical Physics, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece;Department of Physics, University of Ioannina, 45110 Ioannina, Greece;;Department of Skin &

关键词: optical scattering;    optical diffusion;    skin;    cryosurgery;    optical fiber sensors;   

DOI  :  10.3390/app10031053

来源: DOAJ

【 摘 要 】

Cryosurgery/cryotherapy is a widely used, freezing−thawing technique for the renewal or destruction of pathological tissues by applying localized rapid cooling; however, it still relies on the subjective “expert knowledge” of the physicians without, up to now, real-time monitoring of the treatment. This work focused on assessing the depth of freezing using optical transmission and backscattering measurements from frozen/unfrozen porcine ex-vivo skin samples. An optical fiber-array sensor was subsequently developed to determine the depth of freezing and the associated kill zone during freeze−thawing cycles with sub-millimeter accuracy within the skin tissue.

【 授权许可】

Unknown