Development of Vitroceramic Coatings and Analysis of Their Suitability for Biomedical Applications

Coatings

Michael Skokin¹  Sorin-Ion Jinga¹  Izabela Constantinoiu¹  Cristina Busuioc¹  Bogdan-Stefan Vasile¹  Mihaela Bacalum²  Dana Miu³ 

[1] Department of Science and Engineering of Oxide Materials and Nanomaterials, University POLITEHNICA of Bucharest, RO-011061 Bucharest, Romania;Horia Hulubei National Institute of Physics and Nuclear Engineering, RO-077125 Magurele, Romania;National Institute for Laser, Plasma and Radiation Physics, RO-077125 Magurele, Romania;

关键词: vitroceramic;    coatings;    pulsed laser deposition;    bioactivity;    metallic implants;   

DOI  :  10.3390/coatings9100671

来源: DOAJ

【 摘 要 】

Within the field of tissue engineering, thin films have been studied to improve implant fixation of metallic or ceramic materials in bone, connective tissue, oral mucosa or skin. In this context, to enhance their suitability as implantable devices, titanium-based substrates received a superficial vitroceramic coating by means of laser ablation. Further, this study describes the details of fabrication and corresponding tests in order to demonstrate the bioactivity and biocompatibility of the newly engineered surfaces. Thus, the metallic supports were covered with a complex material composed of SiO₂, P₂O₅, CaO, MgO, ZnO and CaF₂, in the form of thin layers via a physical deposition techniques, namely pulsed laser deposition. The resulting products were characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, scanning and transmission electron microscopy coupled with energy dispersive X-ray spectroscopy, selected area electron diffraction, and electron energy loss spectroscopy. It was found that a higher substrate temperature and a lower working pressure lead to the highest quality film. Finally, the samples biocompatibility was assessed and they were found to be bioactive after simulated body fluid soaking and biocompatible through the MTT cell viability test.

【 授权许可】

Unknown