Prognosis after lead extraction in patients with cardiac implantable electronic devices infection: Comparison of lead‐related infective endocarditis with pocket infection in a Japanese single‐center experience

Journal of Arrhythmia

Hiroshi Morimatsu¹  Kazufumi Nakamura²  Hiroshi Ito²  Atsuyuki Watanabe²  Koji Nakagawa²  Yoshimasa Morimoto²  Satoshi Kawada²  Akihito Miyoshi²  Masakazu Miyamoto²  Saori Tsukuda²  Morio Shoda³  Shingo Kasahara⁴  Hiroshi Morita⁵  Nobuhiro Nishii⁵  Nobuchika Kusano⁶ 

[1] Department of Anesthesiology and Resuscitology Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama Japan;Department of Cardiovascular Medicine Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama Japan;Department of Cardiovascular Medicine Tokyo Women's Medical University Tokyo Japan;Department of Cardiovascular Surgery Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama Japan;Department of Cardiovascular Therapeutics Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama Japan;Department of Infectious Disease Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Okayama Japan;

关键词: implantable cardioverter defibrillator;    lead extraction;    lead‐related infective endocarditis;    pacemaker;    pocket infection;   

DOI  :  10.1002/joa3.12164

来源: DOAJ

【 摘 要 】

Abstract Background The increase in the use of cardiac implantable electronic devices (CIEDs) has been associated with an increase in CIED‐related infections. Transvenous lead extraction is safe and effective for patients with CIED‐related infections; however, the mortality rate in these patients is high. The prognosis after transvenous lead extraction in Japanese patients, especially those with lead‐related infective endocarditis, has not been evaluated. Then, the purpose of this study is to clarify the prognosis after transvenous lead extraction in Japanese patients with CIED‐related infections at a single Japanese center. Methods A total of 107 patients who underwent transvenous lead extraction were retrospectively reviewed. The patients were divided into a lead‐related infective endocarditis group (n = 32) and a pocket infection group (n = 75). Procedure success rate and prognosis after lead extraction were evaluated between the two groups. Results Procedure success rate was not significantly different between the groups. There were no deaths associated with the procedure or with infection. The survival rate was not significantly different at 1 year or at a median of 816 days (lead‐related infective endocarditis vs pocket infection; 93.7% vs 94.7%, P = 1.000; 78.1% vs 81.3%, P = 0.791) Time to reimplantation and duration of hospital stay and antibiotics therapy were significantly longer for patients with lead‐related infective endocarditis. Conclusion In this study, the prognosis for patients with lead‐related infective endocarditis after transvenous lead extraction was favorable. Thus, extraction should be strongly recommended, even if the general condition of the patient is poor.

【 授权许可】

Unknown