Data for the effects of rLj-RGD3 on normal tissues of rats and its location in HeyA8 cells

Data in Brief

Li Lv¹  Yue Wang¹  Rong Xiao²  Jihong Wang²  Jianmei Han²  Qi Jiang²  Yuanyuan Zheng²  Yuping Wang² 

[1] Department of Pharmacology, Dalian Medical University, Dalian 116044, PR China;School of Life Sciences, Liaoning Normal University, Dalian 116081, PR China;

关键词: rLj-RGD3;    HeyA8 cells;    Safe evaluation;    Location;   

DOI  :  10.1016/j.dib.2017.03.033

来源: DOAJ

【 摘 要 】

Lj-RGD3 which contains three Arg-Gly-Asp (RGD) motifs was identified from the buccal glands of Lampetra japonica. In the present data article, acute toxicity of recombinant Lj-RGD3 (rLj-RGD3) was performed in Sprague Dawley (SD) rats. Tissue observation data of these SD rats treated with normal saline (NS) or rLj-RGD3 were shown. Furthermore, confocal microscope data were also shown to observe the location of FITC-labeled rLj-RGD3 in the ovarian cancer cells (HeyA8 cells). This paper contains data related to research concurrently published in “rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway” (Q. Jiang, Q. Li, J. Han, M. Gou, Y. Zheng, B. Li, R. Xiao, J. Wang, 2017) [1].

【 授权许可】

Unknown