Insights from the supplementary motor area syndrome in balancing movement initiation and inhibition

Frontiers in Human Neuroscience

Michiel eWagemakers¹  Adriaan R.E. Potgieser¹  Eelco W. Hoving¹  Rob J.M. Groen¹  Bauke M. de Jong¹ 

[1] University Medical Center Groningen;

关键词: Akinetic Mutism;    Neurosurgery;    Parkinson Disease;    Tic Disorders;    Supplementary motor area (SMA);    Supplementary motor area syndrome;   

DOI  :  10.3389/fnhum.2014.00960

来源: DOAJ

【 摘 要 】

The supplementary motor area syndrome is a characteristic neurosurgical syndrome that can occur after unilateral resection of the supplementary motor area. Clinical symptoms may vary from none to a global akinesia, predominantly on the contralateral side, with preserved muscle strength, and mutism. A remarkable feature is that these symptoms completely resolve within weeks to months, leaving only a disturbance in alternating bimanual movements. In this review we give an overview of the old and new insights from the supplementary motor area syndrome and extrapolate these findings to seemingly unrelated diseases and symptoms such as Parkinson’s disease and tics. Furthermore, we integrate findings from lesion, stimulation and functional imaging studies to provide insight in the motor function of the supplementary motor area.

【 授权许可】

Unknown