Modern Pathologic Diagnosis of Renal Oncocytoma

Journal of Kidney Cancer and VHL

Sean R Williamson¹  Sara E Wobker² 

[1] Henry Ford Health System;University of North Carolina at Chapel Hill;

关键词: chromophobe renal cell carcinoma;    kidney;    oncocytic neoplasm;    oncocytoma;    renal mass;    renal mass biopsy;   

DOI  :  10.15586/jkcvhl.2017.96

来源: DOAJ

【 摘 要 】

Oncocytoma is a well-defined benign renal tumor, with classic gross and histologic features, including a tan or mahogany-colored mass with central scar, microscopic nested architecture, bland cytology, and round, regular nuclei with prominent central nucleoli. As a result of variations in this classic appearance, difficulty in standardizing diagnostic criteria, and entities that mimic oncocytoma, such as eosinophilic variant chromophobe renal cell carcinoma and succinate dehydrogenase-deficient renal cell carcinoma, pathologic diagnosis remains a challenge. This review addresses the current state of pathologic diagnosis of oncocytoma, with emphasis on modern diagnostic markers, areas of controversy, and emerging techniques for less invasive diagnosis, including renal mass biopsy and advanced imaging.

【 授权许可】

Unknown