Sudden respiratory failure and eosinophilic pneumonia in patients treated with daptomycin: a report of five cases

Çukurova Üniversitesi Tıp Fakültesi Dergisi

Deniz Tekin¹  Ferit Kuscu²  Aslihan Ulu²  Ayse Seza inal²  Behice Kurtaran²  Yesim Tasova²  Suheyla Komur³ 

[1] Enfeksiyon Hastaliklari/Askim Tufekci Devlet Hastanesi/Adana/Turkiye;Enfeksiyon hastaliklari/Cukurova Universitesi/Adana/Turkiye;Enfeksiyon hastaliklari/Cukurova Universitesi/Adana/Turkiye;

关键词: Daptomycin;    eosinophilic pneumonia;   

DOI  :  10.17826/cutf.208261

来源: DOAJ

【 摘 要 】

Daptomycin is the first member of cyclic lipopeptides came into use in the treatment of resistant gram-positive infections. It is shown to be a good option in the treatment of serious infections caused by gram-positive bacteria. Eosinophilic pneumonia may occur rarely during the use of daptomycin. In this paper we described 5 cases of daptomycin-associated eosinophilic pneumonia. Sudden onset of respiratory failure with tachypnea, tachycardia was observed, peripheral eosinophilia was detected in one patient. The symptoms usually resolved with supportive treatment and after discontinuation of the drug, but steroid treatment and mechanical ventilation was required in some patients. Eosinophilic pneumonia in the sudden onset of respiratory failure should be kept in mind duringdaptomycin treatment. [Cukurova Med J 2016; 41(2.000): 396-399]

【 授权许可】

Unknown