Evidence for the Role of Magnetic Source Imaging in the Presurgical Evaluation of Refractory Epilepsy Patients

Frontiers in Neurology

Hermann Stefan¹  Evelien Carrette² 

[1] Department of Neurology-Biomagnetism, University Hospital Erlangen, Erlangen, Germany;Reference Centre for Refractory Epilepsy, Ghent University Hospital, Ghent, Belgium;

关键词: magnetic source imaging;    refractory epilepsy;    presurgical evaluation;    equivalent current dipole modeling;    magnetoencephalagraphy (MEG);   

DOI  :  10.3389/fneur.2019.00933

来源: DOAJ

【 摘 要 】

Magnetoencephalography (MEG) in the field of epilepsy has multiple advantages; just like electroencephalography (EEG), MEG is able to measure the epilepsy specific information (i.e., the brain activity reflecting seizures and/or interictal epileptiform discharges) directly, non-invasively and with a very high temporal resolution (millisecond-range). In addition MEG has a unique sensitivity for tangential sources, resulting in a full picture of the brain activity when combined with EEG. It accurately allows to perform source imaging of focal epileptic activity and functional cortex and shows a specific high sensitivity for a source in the neocortex. In this paper the current evidence and practice for using magnetic source imaging of focal interictal and ictal epileptic activity during the presurgical evaluation of drug resistant patients is being reviewed.

【 授权许可】

Unknown