Cutaneous Events Associated with Immunotherapy of Melanoma: A Review

Journal of Clinical Medicine

Pietro Quaglino¹  Lorenza Burzi¹  Simone Ribero¹  Bianca Maria Piraccini²  Emi Dika²  Aurora Maria Alessandrini² 

[1] Department of Medical Sciences, Dermatology Clinic, University of Turin, 10126 Turin, Italy;Dermatology, Department of Experimental Diagnostic and Specialty Medicine (DIMES), University of Bologna, 40138 Bologna, Italy;

关键词: melanoma;    immunotherapy;    pigmentation disorders;    vitiligo;    melanosis;    halo nevus;   

DOI  :  10.3390/jcm10143047

来源: DOAJ

【 摘 要 】

Immunotherapy with checkpoint inhibitors significantly improves the outcome for stage III and IV melanoma. Cutaneous adverse events during treatment are often reported. We herein aim to review the principal pigmentation changes induced by immune check-point inhibitors: the appearance of vitiligo, the Sutton phenomenon, melanosis and hair and nail toxicities.

【 授权许可】

Unknown