Nanomaterials-Based Colorimetric Immunoassays

Nanomaterials

Yuanqiang Hao¹  Dehua Deng²  Ning Xia²  Lin Liu² 

[1] Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China;Henan Province of Key Laboratory of New Optoelectronic Functional Materials, Anyang Normal University, Anyang 455000, China;

关键词: colorimetric immunoassays;    nanozymes;    nanoparticle aggregation;    metal ions;    nanomaterials;   

DOI  :  10.3390/nano9030316

来源: DOAJ

【 摘 要 】

Colorimetric immunoassays for tumor marker detection have attracted considerable attention due to their simplicity and high efficiency. With the achievements of nanotechnology and nanoscience, nanomaterials-based colorimetric immunoassays have been demonstrated to be promising alternatives to conventional colorimetric enzyme-linked immunoassays. This review is focused on the progress in colorimetric immunoassays with the signal amplification of nanomaterials, including nanomaterials-based artificial enzymes to catalyze the chromogenic reactions, analyte-induced aggregation or size/morphology change of nanomaterials, nanomaterials as the carriers for loading enzyme labels, and chromogenic reactions induced by the constituent elements released from nanomaterials.

【 授权许可】

Unknown