Fatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement

Revista da Sociedade Portuguesa de Dermatologia e Venereologia

Júlia Vide¹  Sofia Lopes¹  Sofia Magina¹  Filomena Azevedo¹  Ana Paula Cunha¹ 

[1] Serviço de Dermatologia e Venereologia, Centro Hospitalar São João, Porto, Portugal;

关键词: Central Nervous System Diseases;    Orbital Diseases;    Pyoderma Gangrenosum;   

DOI  :  10.29021/spdv.76.4.952

来源: DOAJ

【 摘 要 】

Pyoderma gangrenosum is a chronic inflammatory disease characterized by the development of a painful deep ulcer with undermined borders. Head and neck are rarely affected regions of the body and also usually associated with a worse prognosis. Corticosteroids are the mainstay of treatment although available options are not specific nor completely effective in pyoderma gangrenosum. We report the case of a 46-year-old patient with an aggressive orbital pyoderma gangrenosum with progressive extension to the central nervous system and insufficient response to treatment, ultimately leading to patient’s death.

【 授权许可】

Unknown